STIMULANTS Crack
and Cocaine
Cocaine is a powerfully addictive stimulant
drug. The powdered, hydrochloride salt form of cocaine can be snorted or dissolved
in water and injected. Crack is cocaine that has not been neutralized by an acid
to make the hydrochloride salt. This form of cocaine comes in a rock crystal that
can be heated and its vapors smoked. The term "crack" refers to the crackling
sound heard when it is heated.*
Regardless of how cocaine is used or how
frequently, a user can experience acute cardiovascular or cerebrovascular emergencies,
such as a heart attack or stroke, which could result in sudden death. Cocaine-related
deaths are often a result of cardiac arrest or seizure followed by respiratory
arrest.
Health Hazards Cocaine is a strong central nervous system
stimulant that interferes with the reabsorption process of dopamine, a chemical
messenger associated with pleasure and movement. The buildup of dopamine causes
continuous stimulation of receiving neurons, which is associated with the euphoria
commonly reported by cocaine abusers.
Physical effects of cocaine use
include constricted blood vessels, dilated pupils, and increased temperature,
heart rate, and blood pressure. The duration of cocaine's immediate euphoric effects,
which include hyperstimulation, reduced fatigue, and mental alertness, depends
on the route of administration. The faster the absorption, the more intense the
high. On the other hand, the faster the absorption, the shorter the duration of
action. The high from snorting may last 15 to 30 minutes, while that from smoking
may last 5 to 10 minutes. Increased use can reduce the period of time a user feels
high and increases the risk of addiction. Some users of cocaine report feelings
of restlessness, irritability, and anxiety. A tolerance to the "high" may develop—many
addicts report that they seek but fail to achieve as much pleasure as they did
from their first exposure.
Some users will increase their doses to intensify
and prolong the euphoric effects. While tolerance to the high can occur, users
can also become more sensitive to cocaine's anesthetic and convulsant effects
without increasing the dose taken. This increased sensitivity may explain some
deaths occurring after apparently low doses of cocaine.
Use of cocaine
in a binge, during which the drug is taken repeatedly and at increasingly high
doses, may lead to a state of increasing irritability, restlessness, and paranoia.
This can result in a period of full-blown paranoid psychosis, in which the user
loses touch with reality and experiences auditory hallucinations.
Other
complications associated with cocaine use include disturbances in heart rhythm
and heart attacks, chest pain and respiratory failure, strokes, seizures and headaches,
and gastrointestinal complications such as abdominal pain and nausea. Because
cocaine has a tendency to decrease appetite, many chronic users can become malnourished.
Different means of taking cocaine can produce different adverse effects.
Regularly snorting cocaine, for example, can lead to loss of the sense of smell,
nosebleeds, problems with swallowing, hoarseness, and a chronically runny nose.
Ingesting cocaine can cause severe bowel gangrene due to reduced blood flow. People
who inject cocaine can experience severe allergic reactions and, as with all injecting
drug users, are at increased risk for contracting HIV and other blood-borne diseases. For more information on our South
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Information
contained in this page is courtesy of The National Institute on Drug Abuse (NIDA)
for more information on crack and cocaine please visit: http://www.nida.nih.gov/Infofacts/cocaine.html
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